macrophages

[Gynecological Oncology] Human tumor samples and in vivo patient-derived xenograft and syngeneic murine models were administered Wnt/β-catenin modulating agents DKN-01 and CGX-1321 individually or in sequence

[mBio] Investigators used RNA sequencing to determine that HIV-1 alone induced few or no signs of an type I interferon response in THP-1 cells.

[Cancer Cell International] Data from 471 skin cutaneous melanoma patients in the The Cancer Genome Atlas were analyzed using ESTIMATE algorithms to generate an ImmuneScore, StromalScore, and EstimateScore for each patient.

[Biochemical Pharmacology] Luxeptinib inhibited the release of three cytokines from THP-1 monocytes and macrophages at concentrations of 0.1 µM and above.

[Nanomedicine-Nanotechnology Biology and Medicine] Multifunctional bilayered dermal patches with antibacterial, antioxidant and anti-inflammatory properties were developed and compared for performance. Soluble eggshell membrane protein improved migration of human adult dermal fibroblasts, suggesting its contribution to wound healing.

[Cell Proliferation] Scientists investigate the functional role of hepatic stellate cell ferroptosis in the anti-fibrotic effect of sorafenib and found that sorafenib attenuated liver injury and extracellular matrix accumulation in CCl4-induced fibrotic livers, accompanied by reduction of SLC7A11 and GPX4 proteins.