Luxeptinib Disables NLRP3 Inflammasome-Mediated IL-1β Release and Pathways Required for Secretion of Inflammatory Cytokines IL-6 and TNFα

By
Justin.choi
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0
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Luxeptinib inhibited the release of three cytokines from THP-1 monocytes and macrophages at concentrations of 0.1 µM and above.
[Biochemical Pharmacology]
AbstractGraphical Abstract