malaria

[Chemical Biology & Drug Design] The authors determined the efficacy of pyronaridine in four different NSCLC cell lines and explored its mechanism in H1975.

[Science Advances] Investigators showed remarkably similar transcriptional profiles for atypical B cells (ABCs) clusters in malaria, HIV, and autoimmune diseases and demonstrated that interferon-γ drove the expansion of ABCs in malaria.

[The Journal of Infectious Diseases] Logistic and negative binomial regression were used to assess the impact of maternal peripheral parasitemia, symptomatic malaria, and placental malaria on cord blood maternal microchimerism.

[Mucosal Immunology] The authors review how maternal NK cells balance their double duty both in the local microenvironment of the uterus and systemically, during toxoplasmosis, influenza, cytomegalovirus, malaria and other infections that threat pregnancy.

[Cell Death & Disease] Scientists used a protein conjugation system to produce a bispecific immune engager, V-aCD3, based on recombinant VAR2CSA as the cancer targeting moiety and an anti-CD3 single-chain variable fragment linked to a single-chain Fc as the immune engager.

[npj Vaccines] Researchers describe the development of a platform to supplement existing tools of pre-clinical malaria vaccine development, by displaying linear peptides on a virus-like particle