melanocytes

[Journal of Materials Chemistry B] Investigators selectively conjugated several skin protein-derived cell-targeting peptides, including KTTKS, NAP-amide, and Lam332, to amphiphilic polymer-reinforced lipid nanovesicles to specifically target fibroblasts, melanocytes, and keratinocytes, respectively, through effective association with the corresponding cell membrane receptors.

[Molecular Therapy-Oncolytics] The authors summarize the recent research progress on the effects of non-coding RNAs (ncRNAs) on melanoma and attempt to elucidate the role of ncRNAs as molecular markers or potential targets will provide promising application perspectives of melanoma.

[Scientific Reports] The authors identified a natural acidic formulation to reduce skin pigmentation. The metabolite propionic acid was the most abundant fatty acid in the filtrate from Pluronic F68 fermentation of Cutibacterium acnes and reduced the DOPA-positive melanocytes by significantly inhibiting cellular tyrosinase activity via binding to the free fatty acid receptor 2.

[Cell Death Discovery] Investigators demonstrated that melanocortin-1 receptor (MC1R) is a critical factor in chromosome stability and centromere integrity in melanocytes. α-MSH/MC1R stimulation prevents melanocytes from UV radiation-induced damage of chromosome stability and centromere integrity.

[Scientific Reports] Researchers detected a significantly reduced A375 cell viability, an increase in alanine, inositol, nucleotides, and other metabolites that together define apoptosis.

[Journal of Experimental & Clinical Cancer Research] The authors review the latest progress in hypoxia-regulated pathways involved in the development and progression of all melanoma subtypes.