Tag results:
monocytes
Mesenchymal Cell News
Engineered Delivery of Dental Stem Cell-Derived Extracellular Vesicles for Periodontal Tissue Regeneration
[Advanced Healthcare Materials] Investigators developed a delivery platform for small extracellular vesicles derived from gingival MSCs to treat periodontitis.
Pancreatic Cell News
CCL2-Mediated Monocytes Regulate Immune Checkpoint Blockade Resistance in Pancreatic Cancer
[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.
Pancreatic Cell News
CCL2-Mediated Monocytes Regulate Immune Checkpoint Blockade Resistance in Pancreatic Cancer
[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.
Cell Therapy News
Increased Visceral Fat Distribution and Body Composition Impact Cytokine Release Syndrome Onset and Severity after CD19 CAR-T in Advanced B Cell Malignancies
[Haematologica] Researchers studied the influence of anthropometric and body composition measurements on CAR-T-related immunotoxicity in 64 patients receiving CD19-directed CAR-T for relapsed/refractory B cell malignancies.
Human Immunology News
Single-Cell Isoform Analysis in Human Immune Cells
[Genome Biology] The authors used R2C2 to sequence and demultiplex 12 million full-length cDNA molecules generated by the 10X Genomics platform from ~3000 peripheral blood mononuclear cells.
Immune Regulation News
Glutaredoxin 1 Controls Monocyte Reprogramming during Nutrient Stress and Protects Mice against Obesity and Atherosclerosis in a Sex-Specific Manner
[Nature Communications] The authors reported that in chow-fed, reproductively senescent female mice but not in age-matched male mice, deficiency in the thiol transferase glutaredoxin 1 promoted dysregulated macrophage phenotypes as well as rapid weight gain and atherogenesis.