muscle cells

[Cell Death & Disease] Phenotypic and metabolic profiles with associated cellular signaling pathways involved in lipid metabolism were investigated in the mice heart and human cardiomyocytes to establish treatment effect of adiponectin's agonists.

[Cell Death & Disease] Irisin effectively inhibited β-GP-induced calcium deposition in VSMCs in vitro and in mice aortic rings ex vivo. Overexpression of Nlrp3 attenuated the suppressive effect of Irisin on VSMC calcification.

[Experimental Cell Research] The authors found that lipid transport-associated genes were upregulated in the high interleukin-6 (IL-6) receptor expression group. IL-6 promoted fatty acid uptake in both AML cell lines and primary AML cells.

[Cell Death & Disease] The authors investigated the mechanism of bone marrow MSC-derived exosome using high phosphate stimulated human aortic smooth muscle cells and 5/6 subtotal nephrectomy rat models.

[iScience] Scientists unraveled the substantial contribution of miRNAs in regulating the smooth muscle cell (SMC) transcriptome and identified the miR-200 cluster as a pro-quiescence mechanism and a potential inhibitor of vascular restenosis.

[Annals of Medicine] The authors comprehensively review the role of high-mobility group box 1 (HMGB1), hypoxia-inducible factor-1α (HIF-1α), and VEGF in doxorubicin-induced cardiovascular disease and its molecular mechanisms.