myeloid cells

[Signal Transduction and Targeted Therapy] The authors demonstrated that minks were largely permissive to SARS-CoV-2, characterized by severe and diffuse alveolar damage, and lasted at least 14 days post inoculation.

[Immunology and Cell Biology] Scientists discuss the advances made in asthma research, the pathogenesis of neutrophilic asthma, the mechanisms of progression to severe asthma, risk factors for asthma exacerbations, and biomarkers and treatment of neutrophilic asthma.

[Cancer Discovery] Researchers unveiled the ectonucleotide pyrophosphatase /phosphodiesterase 1 (ENPP1)/HP axis as an unanticipated mechanism exploited by tumor cells linking inflammation to immune remodeling favoring local relapse.

[Hypertension Research] An in vitro cell model was established, followed by a comprehensive evaluation of cell viability and pyroptosis. The binding relationships of miR-378a-3p and ELAVL1, HuR, and NLR family pyrin domain containing 3 were analyzed.

[Current Stem Cell Research & Therapy] The authors explored the contribution of miRNAs in adipose-derived stem cell-extracellular vesicles to the treatment of cerebral ischemia.

[Science Immunology] Investigators reported a critical role of SLAM family receptors, ubiquitously expressed on hematopoietic cells and forming homotypic interactions, in constraining macrophage phagocytosis.