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myeloid cells
Hematopoiesis News
Unique Molecular and Functional Features of Extramedullary Hematopoietic Stem and Progenitor Cell Reservoirs in Humans
[Blood] Researchers comprehensively delineated human extramedullary hematopoietic stem and progenitor cell compartments comparing spleen, peripheral blood (PB) and mobilized PB (mPB) to bone marrow using single-cell RNA-seq and/or functional assays.
Human Immunology News
Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome
[American Journal of Respiratory and Critical Care Medicine] Human and mouse model bronchoalveolar lavage fluid samples were analyzed for the presence and activity of cathepsin S and its endogenous inhibitors.
Human Immunology News
Pan-Cancer Analysis of GALNTs Expression Identifies a Prognostic of GALNTs Feature in Low Grade Glioma
[Journal of Leukocyte Biology] Investigators used Oncomine and The Cancer Genome Atlas databases to analyze the transcription and survival effect of N-acetylgalactosaminyltransferase genes (GALNTs) in pan-cancer.
Human Immunology News
Constructing a Novel Signature Based on Immune-Related lncRNA to Improve Prognosis Prediction of Cervical Squamous Cell Carcinoma Patients
[Reproductive Sciences] Researchers assessed the correlation between immune infiltration status, chemotherapeutics sensitivity, immune checkpoint proteins, and the signature.
Human Immunology News
NLRP3 Inflammasome Activation in Human Peripheral Blood Mononuclear Cells Induced by Venoms Secreted PLAM2s
[International Journal of Biological Macromolecules] Peripheral blood mononuclear cells were isolated by density gradient and incubated with RPMI, LPS, BthTX-I or BthTX-II isolated from Bothrops jararacussu venom, to evaluate viability, and the results showed that there was no cell death.
Human Immunology News
LRG1: An Emerging Player in Disease Pathogenesis
[Journal of Biomedical Science] Emphasis is given to the role that leucine-rich α-2 glycoprotein 1 (LRG1) plays as a vasculopathic factor where it disrupts the cellular interactions normally required for the formation and maintenance of mature vessels, thereby indirectly contributing to the establishment of a highly hypoxic and immunosuppressive microenvironment.