Unique Molecular and Functional Features of Extramedullary Hematopoietic Stem and Progenitor Cell Reservoirs in Humans

Researchers comprehensively delineated human extramedullary hematopoietic stem and progenitor cell compartments comparing spleen, peripheral blood (PB) and mobilized PB (mPB) to bone marrow using single-cell RNA-seq and/or functional assays.