myeloid cells

[Cellular Immunology] Researchers examined tumor-infiltrating lymphocytes in colorectal cancer expressing different levels of SIRT1.

[Cardiovascular Research] NOX1 mediated endothelial activation and contributed to myocardial inflammation and remodeling in metabolic disease in mice. Given its high expression in monocytes of humans with diastolic dysfunction (DD), NOX1 may represent a potential target to mitigate heart disease associated with DD.

[Cell Reports] Analysis of RNA sequencing data, including publicly available datasets, indicated that macrophage fragmentation was a general phenomenon that confounded bulk and single-cell analysis of disaggregated hematopoietic tissues.

[Blood Advances] The authors indicated that Cebpa-enhancer deletion caused cell autonomous neutropenia, which reprogramed and disturbed the quiescence of HSCs, leading to a systemic impairment of the hematopoietic process.

[Blood Advances] Researchers reported results of a phase Ib dose-escalation study of the novel, subcutaneous BET inhibitor RO6870810 combined with the BCL-2 inhibitor venetoclax, and rituximab, in recurrent/refractory diffuse large B cell lymphoma.

[Leukemia Research] Scientists discuss in detail the mechanisms involved in accumulation of cadmium in particular cell lines of the bone marrow and the consequent occurrence of acute myeloid leukemia.