myeloid cells

[Frontiers in Cellular and infection Microbiology] Scientists examined the role of vitamin D deficiency in the regulation of cathelicidin antimicrobial peptide in Crohn’s disease (CD)-like macrophages, including those infected with Mycobacterium avium subsp. paratuberculosis isolated from CD patients.

[PLoS Pathogens] The authors investigated the impact of monocytes, NK cells, and CD8+ T cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type or to the HTLV-1p12KO mutant.

[Heliyon] Investigators identified and ranked clinical and immunological features associated with progression to severe COVID-19 in order to investigate an immunological signature of severe disease.

[Neuroscience and Biobehavioral Reviews] The authors summarize current knowledge on the impact of astrocyte and microglia activity on behavioral outcomes, with a specific focus on brain areas relevant to higher cognitive control, reward-seeking, and circadian regulation.

[Oncogene] The authors evidenced that cholesterol promoted cell proliferation and invasion of lung adenocarcinoma (LAC) in vitro as well as LAC metastasis in vivo.

[Nature Communications] Researchers performed ischemia/reperfusion experiments in mice to assess the impact of genetic ACKR3 deficiency in platelets on tissue injury in ischemic myocardium and brain.