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myeloid cells

Single-Cell RNA Sequencing Reveals Distinct Tumor Microenvironmental Patterns in Lung Adenocarcinoma

[Oncogene] To identify clinically relevant microenvironmental and cancer features, scientists applied single-cell RNA sequencing to ten human lung adenocarcinomas and ten normal control tissues.

Regulatory Association of Long Noncoding RNAs and Chromatin Accessibility Facilitates Erythroid Differentiation

[Blood Advances] The authors employed HSCs, multipotent progenitor cells, common myeloid progenitor cells, megakaryocyte-erythroid progenitor cells, and erythroblasts from human cord blood as an erythroid differentiation model to explore the coordinated regulatory functions of lncRNAs and chromatin accessibility by integrating RNA-Seq and ATAC-Seq data.

Human Induced Pluripotent Stem Cell-Derived Platelets Loaded with Lapatinib Effectively Target HER2+ Breast Cancer Metastasis to the Brain

[Scientific Reports] Investigators described methods for ex vivo generation of megakaryocytes and functional platelets from human induced pluripotent stem cells in a scalable fashion.

Cardiac Resident Macrophages Prevent Fibrosis and Stimulate Angiogenesis

[Circulation Research] Researchers assessed the role of cardiac immune cells in the early hypertrophy response to cardiac pressure overload-induced by transverse aortic constriction.

Novel Scaffold Based Graphene Oxide Doped Electrospun Iota Carrageenan/Polyvinyl Alcohol for Wound Healing and Pathogen Reduction: In Vitro and In Vivo Study

[Scientific Reports] Scientists worked with electrospun nanofiber scaffold named that was composed of polyvinyl alcohol/iota carrageenan and doped with partially reduced graphene oxide that was successfully synthesized for wound healing and skin repair.

AXL Cooperates with EGFR to Mediate Neutrophil Elastase-Induced Migration of Prostate Cancer Cells

[iScience] Scientists reported that neutrophil elastase triggered dose-dependent ERK signaling and cell migration in a panel of prostate cell lines representing the spectrum of prostate cell malignancy.

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