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myeloid cells

Leukemic Progenitor Cells Enable Immunosuppression and Post-Chemotherapy Relapse via IL-36–Inflammatory Monocyte Axis

[Science Advances] Researchers showed that abnormal IL-36 production activated by NF-κB was an essential feature of mouse and human leukemic progenitor cells.

Targeting of the Tumor Immune Microenvironment by Metformin

[Journal of Cell Communication and Signaling] The authors explain the basic mechanisms for the interactions and communications between immunosuppressive, anti-tumoral, and cancer cells within the tumor microenvironment (TME), and discuss the modulating effects of metformin on various cells and secretions in the TME.

Mechanism of Neutrophil Extracellular Traps Generation and Their Role in Trophoblast Apoptosis in Gestational Diabetes Mellitus

[Cellular Signalling] The authors revealed the mechanism of neutrophil extracellular traps generation and their role in trophoblast apoptosis in gestational diabetes mellitus.

CCL11 Exacerbates Colitis and Inflammation-Associated Colon Tumorigenesis

[Oncogene] Scientists showed that CCL11 was involved in the pathogenesis of dextran sulfate sodium (DSS)-induced colitis and in colon tumorigenesis in the azoxymethane-DSS model of colitis-associated carcinogenesis.

Fermented Food Tempeh Induces Interleukin 12 and Enhances Macrophage Phagocytosis

[Journal of Food Biochemistry] Researchers investigated the IL-12 inducibility of fermented foods using the specific antibody. Fermented soybean foods such as Tempeh and Natto are attracting attention in terms of nutrition, functionality, and food problems.

Eosinophil Extracellular Traps Drive Asthma Progression through Neuro-Immune Signals

[Nature Cell Biology] Scientists showed that eosinophil extracellular traps in bronchoalveolar lavage fluid are associated with the severity of asthma in patients.

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