myocardial infarction

[Bayer, Inc.] Bayer announced that the US FDA has approved finerenone, the first non-steroidal, selective mineralocorticoid receptor (MR) antagonist, under the brand name Kerendia®.

[Scientific Reports] The authors used X-ray Phase Contrast Imaging to comprehensively quantify ischemic remodeling of different myocardial structures, from cell to organ level, in a rat model of myocardial infarction.

[Laboratory Investigation] The authors investigated the role of hypoxia/serum deprivation-induced M1-type macrophage-derived exosomes on bone marrow MSC viability, migration, and apoptosis.

[Science Translational Medicine] Researchers investigated an adeno-associated virus 9–based gene therapy to locally knock down the Hippo pathway gene Salvador in border zone cardiomyocytes in a pig model of ischemia/reperfusion-induced myocardial infarction.

[European Journal of Pharmacology] Researchers studied atorvastatin effects on the angiogenesis-signaling pathways from MSCs' differentiation to tissue angiogenesis.

[Scientific Reports] Investigators demonstrated that, in an in vitro setting, MAPC cells increase Treg frequencies by promoting Treg proliferation and CD4+ T cell differentiation into Tregs.