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neural cells

Tumor Suppressive Effects of miR-124 and Its Function in Neuronal Development

[International Journal of Molecular Sciences] Investigators summarize the anti-tumor effects of miR-124. They then discuss the functions of miR-124 with that of its original role in neurons.

Cell Adhesion Factors in the Orbitofrontal Cortex Control Cue-Induced Reinstatement of Cocaine Seeking and Amygdala-Dependent Goal Seeking

[Journal of Neuroscience] Investigators locally ablated neuronal β1-integrins, cell adhesion receptors that adhere cells to the ECM and thus support dendritic spine stability.

A Selective Cytotoxic Adenovirus Vector for Concentration of Pluripotent Stem Cells in Human Pluripotent Stem Cell-Derived Neural Progenitor Cells

[Scientific Reports] Researchers investigated whether a generation of an adenovirus vectors that possess a suicide gene allow for detection of undifferentiated human iPSCs in preparations of human iPSC-derived neural progenitor cells, which have been expected to treat neurological disorders.

Upregulation of Apol8 by Epothilone D Facilitates the Neuronal Relay of Transplanted NSCs in Spinal Cord Injury

[Stem Cell Research & Therapy] Epothilone D could promote the neuronal differentiation of neural stem cells by upregulating Apol8, which might provide a promising therapeutic target for spinal cord injury repair.

Optimal Conditions for Graft Survival and Reinnervation of Denervated Muscles after Embryonic Motoneuron Transplantation into Peripheral Nerves Undergoing Wallerian Degeneration

[Journal of Tissue Engineering and Regenerative Medicine] The authors investigated whether functional reinnervation of denervated muscle could be achieved by early or delayed transplantation after denervation.

Glycoproteomic Analysis of the Changes in Protein N-Glycosylation during Neuronal Differentiation in Human-Induced Pluripotent Stem Cells and Derived Neuronal Cells

[Scientific Reports] Researchers conducted sequential LC/MS/MS analyses of tryptic digest, enriched glycopeptides, and deglycosylated peptides of proteins derived from human iPSCs and iPSC-derived neuronal cells, which were used as a model of neuronal differentiation.

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