Glycoproteomic Analysis of the Changes in Protein N-Glycosylation during Neuronal Differentiation in Human-Induced Pluripotent Stem Cells and Derived Neuronal Cells

Researchers conducted sequential LC/MS/MS analyses of tryptic digest, enriched glycopeptides, and deglycosylated peptides of proteins derived from human iPSCs and iPSC-derived neuronal cells, which were used as a model of neuronal differentiation.