neural stem cells

[Cell Reports] Scientist found that FGF13A, the nuclear isoform of FGF13, is involved in the maintenance of neural stem cells and the suppression of neuronal differentiation during post-natal hippocampal development.

[Cell & Bioscience] Researchers describe the cellular and molecular properties of urine-derived stem cells, their differentiation potency, different reprogramming methods for the generation of iPSCs/induced neural stem cells, and their potential applications in modeling neurological diseases.

[Scientific Reports] Investigators utilized a neonatal rat model of bronchopulmonary dysplasia to assess if hyperoxia stimulates lung release of circulating extracellular vesicles(EVs) and if these EVs induce lung and brain injury.

[Developmental Cell] The authors performed single-cell transcriptomics to define embryonic hypothalamic microglia heterogeneity and identified four microglial subsets, including a subpopulation adjacent to neural stem cells that was responsive to gestational cold stress.

[Nature Metabolism] Scientists identified radial glia-like neural stem cell population with high Irx3 and Irx5 expression in early postnatal hypothalamus and demonstrated that reduced dosage of Irx3 and Irx5 promoted neurogenesis in postnatal hypothalamus leading to elevated numbers of leptin-sensing arcuate neurons.

[Cell Stem Cell] Scientists pinpoint multiple factors that disrupted neural stem cell (NSC) behavior in the adult hippocampus. Clonal tracing showed that NSCs exhibited asynchronous depletion by identifying short-term NSCs and long-term NSCs.