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neutrophils

The Non-ELR CXC Chemokine Encoded by Human Cytomegalovirus UL146 Genotype 5 Contains a C-Terminal β-Hairpin and Induces Neutrophil Migration as a Selective CXCR2 Agonist

[PLoS Pathogens] Researchers investigated how the diversity of UL146 in Human cytomegalovirus affected its signaling and structural properties to understand why its genetic diversity is maintained across human populations.

Dendritic Cells a Critical Link to Alveolar Bone Loss and Systemic Disease Risk in Periodontitis: Immunotherapeutic Implications

[Periodontology 2000] Dendritic cells consist of multiple subsets that reside in the epithelium, connective tissues, and major organs.

Differential Impact of JUUL Flavors on Pulmonary Immune Modulation and Oxidative Stress Responses in Male and Female Mice

[Archives of Toxicology] The author discusses the increase in circulating follicular helper T cells seen in autoimmune settings and explores potential explanations for this phenomenon.

Mesenchymal Stem Cells Protect against Acetaminophen Hepatotoxicity by Secreting Regenerative Cytokine Hepatocyte Growth Factor

[Stem Cell Research & Therapy] MSCs were comparable to N-acetylcysteine against acetaminophen (APAP)-induced liver failure by secreting hepatocyte growth factor with less regenerative retardation concerns, thus facilitating the application of MSCs in clinical therapy for APAP liver failure.

Necroptosis Triggers Spatially Restricted Neutrophil-Mediated Vascular Damage during Lung Ischemia Reperfusion Injury

[Proceedings of the National Academy of Sciences of the United States of America] Researchers found that TLR4 signaling in vascular endothelial cells and downstream NADPH oxidase 4 expression mediate the arrest of neutrophils, a step upstream of their extravasation.

Single-Cell Analysis of Skin Immune Cells Reveals an Angptl4-ifi20b Axis That Regulates Monocyte Differentiation during Wound Healing

[Cell Death & Disease] The authors performed flow cytometry and single-cell RNA sequencing to examine the immune cell landscape of excisional wounds from Angptl4+/+ and Angptl4−/− mice.

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