organoids

[Ophthalmology Times] Dr. Steven DeVries, a professor of Ophthalmology at the University of Wisconsin, has received an International Research Collaborators Award from Research to Prevent Blindnes that will allow him to learn from scientists at Ritsumeikan University in Japan about the process of growing 3D retinal organoids from stem cells.

[Nature Cell Biology] Researchers demonstrated that human alveolar type 2 cells (hAEC2s), unlike murine AEC2s, transdifferentiated into basal cells in response to fibrotic signaling in the lung mesenchyme, in vitro and in vivo.

[International Journal of Oral Science] Scientists identified a molecular mechanism in iPSCs responding to intermittent compressive force by analyzing the global gene expression profile.

[Cell Reports] Researchers generated human fallopian tube epithelial (FTE) organoids from BRCA1 mutation carriers that provided a faithful physiological in vitro model of FTE lesion generation and early carcinogenesis.

[Inflammatory Bowel Diseases] Induced pluripotent stem cells from two control individuals and two very early onset inflammatory bowel disease patients with structuring complications were obtained and directed to form human intestinal organoids.

[Translational Oncology] Investigators generated a prospective cohort of 27 consecutive biopsied derived pancreatic organoids and included them in the signature identification strategy.