pancreatitis

[Biochemical Genetics] The authors studied the mechanism of miR-122 in regulating intestinal barrier function in acute pancreatitis (AP). AP rat model was constructed via intraperitoneal injection of ketamine, and primary intestinal epithelial cells were isolated from rats for in vitro studies.

[npj Precision Oncology] In vitro and ex vivo analyses of pentraxin 3, in human PDAC samples, pancreatic stellate cells (PSCs), cell lines and transgenic mouse model for PDAC, suggested that pentraxin 3 originated from stromal cells, mainly PSCs.

[Current Opinion in Gastroenterology] The authors review recent efforts about standardized imaging features and reporting of chronic pancreatitis and recently published or ongoing imaging studies, which aim to establish novel imaging biomarkers for detection of parenchymal changes seen in chronic pancreatitis.

[Toxicology Letters] Investigators suggested that nicotine has the potential to facilitate pancreatic fibrosis in chronic pancreatitis.

[Chemico-Biological interactions] The effects of prodrug 1 were studied in lipopolysaccharide-induced in vitro and in vivo apoptosis and pancreatitis models by determining the cellular apoptotic levels with human umbilical vein endothelial cells and pancreatic caspase-3/-7 activity in mice.

[Scientific Reports] Scientists investigated the role of discoidin domain receptors in chronic pancreatitis.