protein expression

[Scientific Reports] Investigators utilized in vitro transcribed mRNA to introduce Na+-taurocholate-cotransporting polypeptide (NTCP) into cells. After transfection of mRNA, surface expression and functionality of NTCP was demonstrated by staining with an N-terminal HBV-preS peptide and bile acid uptake.

[Journal of Biological Chemistry] USP10 expression was detected in mouse arteries and increased after carotid ligation. In vitro data showed that USP10 deficiency reduced proliferation and migration of rat thoracic aorta smooth muscle cells (A7r5) and human aortic smooth muscle cells (HASMCs).

[Modern Pathology] In this review, scientists address the state of PD-L1 testing in lung cancer, the role for tumor mutation burden as a predictive biomarker

[Scientific Reports] Scientists demonstrated that short-term exposure to BMP7 decreased the fibrocartilage chondrocyte phenotype. The BMP7-dependent reduction of Collagen type I protein expression seemed MMP2-dependent and inhibition of Smad2/3-PAI1 activity was identified as a potential pathway via which BMP7 exerted its anti-fibrotic action.

[Stem Cell Reviews and Reports] The impact of 3D co-culture of human fetal pancreatic-derived mesenchymal cells with human embryonic stem cell-derived pancreatic progenitors development towards endocrine and beta cells was assessed.

[Cancer Medicine] SEC61G expression was analyzed using publicly available datasets. The association between SEC61G and disease prognosis was evaluated.