regulatory T cells

[Molecular Biology Reports] A considerable number of studies suggest that the role of indoleamine 2,3 dioxygenase in T helper 2 cell regulation may be different from that of T helper 1 immune responses.

[Stem Cell Research & Therapy] The impact of human MuStem cells or their secretome on the proliferative and phenotypic properties of T cells was explored by co-culture experiments with either peripheral blood mononucleated cells or CD3-sorted T cells.

[Cancer] Researchers review the role of tumor-infiltrating Tregs in tumor progression and metabolic reprogramming of the tumor microenvironment.

[Molecular Therapy Oncolytics] The authors compared second-generation with third-generation carbonic anhydrase IX targeted CAR constructs and investigated the anti-tumor effect of CAR-T cells with different CD4/CD8 proportions in vitro and in vivo.

[Science Translational Medicine] Investigators evaluated the B cell subsets, Breg cell function, and the effect of B cell depletion therapy on these cells in patients with neuromyelitis optica spectrum disorder.

[Hypertension Research] Using multicolor flow cytometry, expression of maturation markers in total dendritic cells (DCs), myeloid DCs, and plasmacytoid DCs and the distribution of peripheral Th17-bearing and T-reg cells were defined.