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regulatory T cells

Mucosal Tissue Regulatory T Cells Are Integral in Balancing Immunity and Tolerance at Portals of Antigen Entry

[Mucosal Immunology] Scientists summarize current knowledge regarding mucosal Tregs in both health and disease.

A TNFR2 Antibody by Countering Immunosuppression Cooperates with HMGN1 and R848 Immune Stimulants to Inhibit Murine Colon Cancer

[International Immunopharmacology] Scientists examined the efficacy of TY101 as an anti-tumor immune reagent combined with HMGN1and R848.

The Kynurenine Pathway in Acute Kidney Injury and Chronic Kidney Disease

[American Journal of Nephrology] Investigators summarize the roles of the kynurenine pathway and its metabolites in acute kidney injury and chronic kidney disease based on current literature evidence.

Oncolytic Adenovirus Inhibits Malignant Ascites of Advanced Ovarian Cancer via Reprograming Ascitic Immune Microenvironment

[Molecular Therapy-Oncolytics] Scientists found that oncolytic adenovirus conferred an effective ability to reduce ascites development and prolong overall survival.

A Novel Cytokine Consisting of the p40 and EBI3 Subunits Suppresses Experimental Autoimmune Arthritis via Reciprocal Regulation of Th17 and Treg Cells

[Cellular & Molecular Immunology] The presence of the p40-EBI3 heterodimer was confirmed by ELISA, immunoprecipitation, and western blotting. A p40-EBI3 vector and p40-EBI3-Fc protein were synthesized to confirm the immunological role of this protein in mice with collagen-induced arthritis

A Regulatory T Cell Signature Distinguishes the Immune Landscape of COVID-19 Patients from Those with Other Respiratory Infections

[Science Advances] Scientists compared the immune signature from hospitalized SARS-CoV-2–infected patients to patients hospitalized prepandemic with influenza or respiratory syncytial virus.

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