SARS-CoV-2

[Biomaterials] The basal layer cells of tonsil epithelial cell–derived organoids expressed molecules essential for SARS-CoV-2 entry, such as angiotensin-converting enzyme 2, transmembrane serine protease 2 and furin, being susceptible to the viral infection.

[Blood Advances] Recipients of hematopoietic stem cell transplantation showed weaker immune responses to COVID-19 vaccines than healthy controls

[iScience] Compared to using MSCs or rh-ACE2 alone, the administration of ACE2-MSCs much more significantly reduced inflammatory factors and pyroptosis factors and alleviated lung injury in vivo and in vitro, which might have been due to the increased activities of secretory ACE2.

[Ebiomedicine] Scientists summarize the major pathological characteristics of COVID-19 and provide scientific and rational evidence for the safety and possible effectiveness of MSCs in COVID-19 treatment.

[eLife] An observational study found that the abundance of innate lymphoid cells decreased more than 7-fold over the human lifespan - T cell subsets decreased less than two-fold - and is lower in males than in females.

[Signal Transduction and Targeted Therapy] Scientists confirmed that SARS-CoV-2 viral antigen could be detected in patient peripheral blood cells or postmortem lung T cells, and the infectious virus could also be detected from viral antigen-positive PBCs.