Tag results:
SARS-CoV-2
Mesenchymal Cell News
Mesenchymal Stem Cell Treatment Improves Outcome of COVID-19 Patients via Multiple Immunomodulatory Mechanisms
[Cell Research] MSC infusion reduced the levels of C-reactive protein, proinflammatory cytokines, and neutrophil extracellular traps, and promoted the maintenance of SARS-CoV-2-specific antibodies.
Human Immunology News
Single-Cell Profiling of Proteins and Chromatin Accessibility Using PHAGE-ATAC
[Nature Biotechnology] Researchers developed PHAGE-Assay for Transposase-Accessible Chromatin (ATAC), a massively parallel droplet-based method that used phage displaying, engineered, camelid single-domain antibodies for simultaneous single-cell measurements of protein levels and chromatin accessibility profiles, and mitochondrial DNA-based clonal tracing.
Immunology of Infectious Disease News
GRAd-COV2, a Gorilla Adenovirus-Based Candidate Vaccine against COVID-19, Is Safe and Immunogenic in Younger and Older Adults
[Science Immunology] The authors described a COVID-19 vaccine based on a replication-defective gorilla adenovirus expressing the stabilized pre-fusion SARS-CoV-2 spike protein, named GRAd-COV2.
Immunology of Infectious Disease News
Identification of Driver Genes for Critical Forms of COVID-19 in a Deeply Phenotyped Young Patient Cohort
[Science Immunology] Investigators employed a multi-omics analysis combined with artificial intelligence in a young patient cohort where major comorbidities were excluded at the onset.
Immunology of Infectious Disease News
Membrane Fusion and Immune Evasion by the Spike Protein of SARS-CoV-2 Delta Variant
[Science] Investigators reported the structure, function, and antigenicity of the SARS-CoV-2 Delta variant's full-length spike trimer and those of the Gamma and Kappa variants and compared their characteristics with the G614, Alpha, and Beta variants.
Immunology of Infectious Disease News
Immune Memory from SARS-CoV-2 Infection in Hamsters Provides Variant-Independent Protection but Still Allows Virus Transmission
[Science Immunology] Scientists demonstrated that engagement of the innate immune system following SARS-CoV-2 infection was delayed but was followed by a pronounced adaptive response.