SARS-CoV-2

[Cell] Scientists identified 24 full-length coronavirus genomes, including four novel SARS-CoV-2 related and three SARS-CoV related viruses.

[Hypertension Research] After the COVID-19 era, the novel vaccine technology developed will expand to other vaccines. Scientists have been developing vaccines for chronic diseases, such as hypertension, for over ten years.

[Nature Communications] Scientists demonstrated that despite the large size of the viral RNA genome, infectious full-length cDNA is readily assembled in vitro by a circular polymerase extension reaction methodology without the need for technically demanding intermediate steps.

[Nature Communications] To understand the structural basis for SARS-CoV-2 viral-host protein recognition, scientists used cryo-electron microscopy to determine a complex structure of the human cell junction protein PALS1 and SARS-CoV-2 viral envelope protein.

[Cardiovascular Drugs and Therapy] The clinical features of COVID-19, the central role of the endothelium in COVID-19 and in other pathologies, and the potential of specific therapies aimed at protecting the endothelium in COVID-19 patients are addressed.

[Trends in Biochemical Sciences] Investigators discuss the recent advancement in understanding the molecular events during SARS-CoV-2 entry which would contribute to developing vaccines and therapeutics.