To understand the structural basis for SARS-CoV-2 viral-host protein recognition, scientists used cryo-electron microscopy to determine a complex structure of the human cell junction protein PALS1 and SARS-CoV-2 viral envelope protein.
[Nature Communications]
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Chai, J., Cai, Y., Pang, C., Wang, L., McSweeney, S., Shanklin, J., & Liu, Q. (2021). Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1. Nature Communications, 12(1), 3433. https://doi.org/10.1038/s41467-021-23533-x Cite