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squamous cell carcinoma

Onconova Announced First Patient Dosed in Investigator-Initiated Phase II Study of Rigosertib in Recessive Dystrophic Epidermolysis Bullosa-Associated Squamous Cell Carcinoma

[Onconova Therapeutics, Inc. (GLOBE NEWSWIRE)] Onconova Therapeutics, Inc., announced that the first patient has been dosed in an investigator-initiated Phase II study to assess the efficacy and safety of rigosertib in patients with recessive dystrophic epidermolysis bullosa-associated locally advanced/metastatic squamous cell carcinoma.

HEATR1, a Novel Interactor of Pontin/Reptin, Stabilizes Pontin/Reptin and Promotes Cell Proliferation of Oral Squamous Cell Carcinoma

[Biochemical and Biophysical Research Communications] Researchers identified HEAT repeat-containing protein 1 (HEATR1) as a novel binding factor of Pontin/Reptin.

CD44v6-Targeted CAR T-cells Specifically Eliminate CD44 Isoform 6 Expressing Head/Neck Squamous Cell Carcinoma Cells

[Oral Oncology] Scientists established a highly specific chimeric antigen receptors (CAR) against CD44v6 on head and neck squamous cell carcinoma cells that can be expressed on normal T-cells with lentiviral vectors.

Prion Protein Is Associated with a Worse Prognosis of Head and Neck Squamous Cell Carcinoma

[Journal of Oral Pathology & Medicine] Scientists investigated hypoxia's effect in lymph node metastasis by prion protein expression changes and its main partners.

Downregulated hsa_circ_0036988 Promotes Proliferation and Metastasis in Oral Squamous Cell Carcinoma

[Cancer Biomarkers] The study investigated the potential function of a candidate circRNA hsa_circ_0036988 in oral squamous cell carcinoma

Exploring the Dermotoxicity of the Mycotoxin Deoxynivalenol: Combined Morphologic and Proteomic Profiling of Human Epidermal Cells Reveals Alteration of Lipid Biosynthesis Machinery and Membrane...

[Archives of Toxicology] To investigate the potential dermotoxicity of Deoxynivalenol (DON), epidermoid squamous cell carcinoma cells A431 were compared to primary human neonatal keratinocytes (HEKn) cells via proteome/phosphoproteome profiling.

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