Exploring the Dermotoxicity of the Mycotoxin Deoxynivalenol: Combined Morphologic and Proteomic Profiling of Human Epidermal Cells Reveals Alteration of Lipid Biosynthesis Machinery and Membrane Structural Integrity Relevant for Skin Barrier Function

0
213
To investigate the potential dermotoxicity of Deoxynivalenol (DON), epidermoid squamous cell carcinoma cells A431 were compared to primary human neonatal keratinocytes (HEKn) cells via proteome/phosphoproteome profiling.
[Archives of Toxicology]
Del Favero, G., Janker, L., Neuditschko, B., Hohenbichler, J., Kiss, E., Woelflingseder, L., Gerner, C., & Marko, D. (2021). Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane structural integrity relevant for skin barrier function. Archives of Toxicology. https://doi.org/10.1007/s00204-021-03042-y Cite
Full Article