Publication

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Researchers investigated hidradenitis suppurativa epithelial cells and demonstrated that hidradenitis suppurativa basal progenitors modulated their lineage restriction and gave rise to pathogenic keratinocyte clones, resulting in epidermal hyperproliferation and dysregulated inflammation.

[Journal Of Translational Medicine] A novel hybrid murine model of lung cancer with interstitial pneumonia was established via bleomycin-induced pulmonary fibrosis followed by orthotopic lung cancer cell transplantation into the lungs.

[Biomedicine & Pharmacotherapy] Both lipopolysaccharides-induced mouse and alveolar organoid acute lung injury models were established to confirm the potential therapeutic effect of mesenchymal stem cells secreted keratinocyte growth factor (KGF).

[JCI Insight] Scientists determined if use of lactate relative to magnetic antibody-based cell sorting-purified human induced pluripotent stem cell (hiPSC)–derived cardiomyocytes impacted the properties of resulting hiPSC-engineered cardiac tissues.

[Oncogene] Transcriptome profiling combined to bioinformatic analyses disclosed a gene signature commonly regulated by DHX9 and the lysine demethylase KDM2B, with the Hippo pathway regulator YAP1 as a prominent target in Ewing sarcoma.

[Molecular Neurobiology] Researchers studied the possible benefits of combining tauroursodeoxycholic acid with bone marrow MSC transplantation using an animal model of spinal cord injury.