Publication

[Cancer Gene Therapy] Scientists investigated the role and mechanism of long non-coding RNAs in regulating the interaction between melanoma CSCs and non-CSCs during the metastatic colonization process.

[Scientific Reports] Scientists investigated the impact of SIRT6-overexpression in Delta16HER2 mice, which were a bona fide model of HER2-positive breast cancer.

[Neuro-Oncology] Researchers explored acetate from glioblastoma cells, which triggered reactive astrogliosis in neighboring astrocytes by upregulating MAO-B and MCT1 expression.

[Journal of Neuro-Oncology] The authors investigated the molecular mechanism that induce stem cell features in spinal ependymoma (SE). They found that RFX2 activates PAF1 transcription, which promoted tumor stemness of SE cells and led to the malignant progression of SE.

[Nature Structural & Molecular Biology] By combining NMR, biochemistry and cell biology techniques, scientists found that talin and kindlin binding to the β-tail could induce a conformational change that increased talin affinity and decreases kindlin affinity toward it.

[Scientific Reports] Researchers examined whether the inhibition of bundling of collagen fibrils using a potent lysyl oxidase inhibitor, β-aminopropionitrile changed the cellular network of the chick calvaria.