Review

[Amino Acids] Investigators highlight evidence that supports the relative preservation of amino acid-stimulated insulin secretion compared to glucose-stimulated insulin secretion in type 2 diabetes, and make the case for the therapeutic potential of amino acids.

[Immunology] The authors summarize the role of IL-2 or IL-2 complexes in viral infections as well as the application of ld-IL-2 in the context of autoimmune diseases combined with viral infections.

[Cell Death & Differentiation] The authors highlight current challenges and potential future directions in the study of RNA modifications in MSCs, emphasizing the need for innovative tools to precisely map these modifications and decipher their context-specific effects.

[Blood] Prior to and during pregnancy, in addition to the assessment and care that every pregnant patient should receive, patients with sickle cell disease should be evaluated and treated by a multidisciplinary team with respect to their unique maternal and fetal issues.

[Stem Cell Reports] The authors increased functionality of cells derived from fetal tissues arises from increased proliferative capacity, ability to survive in culture, and developmental potential that is attenuated in adult tissues.

[JAMA Oncology] Investigators focus on linking the efficacy and safety of CAR T cell therapy with tumor burden. Emerging clinical approaches to overcome these obstacles and more effectively incorporate this therapeutic strategy into the treatment paradigm of patients with solid malignant tumors are also described.