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Mesenchymal Cell News
Evaluation of In Vivo and Ex Vivo Pre-Treated Bone Marrow-Derived Mesenchymal Stem Cells with Resveratrol in Streptozotocin-Induced Type 1 Diabetic Rats Get Access Arrow
[Journal Of Pharmacy And Pharmacology] Type-1 diabetes was induced by a single streptozotocin injection in 24 rats. Following the confirmation of type 1 diabetes mesenchymal, diabetic rats were randomly divided into four groups: diabetic control, diabetic rats treated with insulin subcutaneous, diabetic rats treated with MCR cells and diabetic rats treated with bone marrow-MSCs isolated from resveratrol-pre-treated rats cells.
Mesenchymal Cell News
A Pumpless Monolayer Microfluidic Device Based on Mesenchymal Stem Cell-Conditioned Medium Promotes Neonatal Mouse In Vitro Spermatogenesis
[Stem Cell Research & Therapy] The authors generated a novel, pumpless, single polydimethylsiloxane-layered testis-on-chip platform providing a continuous and stabilized microfluidic flow and real-time cellular paracrine contribution of allogeneic bone marrow-derived MSCs.
Mesenchymal Cell News
Intra-individual Variability in the Neuroprotective and Promyelinating Properties of Conditioned Culture Medium Obtained from Human Adipose Mesenchymal Stromal Cells
[Stem Cell Research & Therapy] Researchers characterized the individual variability of the secretome of adipose tissue-derived MSCs with regard to potential therapeutical applications in neurology.
Extracellular Matrix News
Phase-Separation Facilitated One-Step Fabrication of Multiscale Heterogeneous Two-Aqueous-Phase Gel
[Nature Communications] The authors presented a one-step fabrication method based on aqueous phase separation to construct two-aqueous-phase gels that comprise multiple phases with distinct physicochemical properties.
Immune Regulation News
Oncolytic Therapy with Recombinant Vaccinia Viruses Targeting the Interleukin-15 Pathway Elicits a Synergistic Response
[Molecular Therapy Oncolytics] Scientists demonstrated that the admixture of these recombinant variants could promote the generation of the IL15/IL15Rα complex.
Immune Regulation News
Asymmetric Cell Division Safeguards Memory CD8 T Cell Development
[Cell Reports] Scientists found that strong T cell receptor stimulation induces elevated asymmetric cell division rates, and subsequent single-cell-derived colonies comprise both effector and memory precursor cells.