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Review

Phenotypic Switching of Vascular Smooth Muscle Cells in Atherosclerosis

[Journal Of The American Heart Association] The authors discuss the nine vascular smooth muscle cell (VSMC) phenotypes that have been reported in atherosclerotic lesions and classify them into differentiated VSMCs, intermediately dedifferentiated VSMCs, and dedifferentiated VSMCs.

(B)On(e)-Cohistones and the Epigenetic Alterations at the Root of Bone Cancer

[Cell Death & Differentiation] The authors critically assess existing literature on oncohistones focussing mainly on bone neoplasms.

The Evolving Landscape of B Cells in Cancer Metastasis

[Cancer Research] Scientists review the complex roles of B cells in metastasis, delineating the heterogeneity of B cell activity and subtypes by metastatic site, antibody class, antigen, and molecular phenotype.

Cardinal Features of Immune Memory in Innate Lymphocytes

[Nature Immunology] It is now appreciated that innate lymphocytes possess memory properties akin to those of adaptive immune cells.The authors draw parallels from T cell biology to explore the key features of immune memory in innate lymphocytes, including quantity, quality, and location.

INSPIRED Symposium Part 4A: Access to CAR T cell Therapy in Unique Populations with B-Cell Acute Lymphoblastic Leukemia

[Transplantation And Cellular Therapy] It is important to prospectively study patient-reported outcomes given the differential toxicity expected between CD19 CAR T cell therapy and the historic standard of care, hematopoietic cell transplant.

The Role of NFATc1 in the Progression and Metastasis of Prostate Cancer: A Review on the Molecular Mechanisms and Signaling Pathways

[Cell Biology International] The authors highlight the role of NFATc1 in the progression and metastasis of prostate cancer and summarize the signaling pathways and molecular mechanisms, through which NFATc1 regulates the process of prostate cancer.

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