Review

[Bioscience Reports] A literature search was conducted using scientific search engines, PubMed, MEDLINE, and google scholar databases with the terms “Cartilage tissue engineering” and “ stem cells” to retrieve published literature on chondrogenic differentiation and tissue engineering using MSCs, ESCs, and hiPSCs.

[Nature Reviews Rheumatology] In rheumatoid arthritis, juvenile idiopathic arthritis and other forms of inflammatory arthritis, the immune system targets certain joints but not others. The pattern of joints affected varies by disease and by individual, with flares most commonly involving joints that were previously inflamed.

[Journal Of Translational Medicine] The authors discuss the role of melanocytes in homeostasis and disease, before discussing their potential in regenerative medicine applications, such as for disease modeling, drug testing, or therapy development using stem cell technologies, tissue engineering, and extracellular vesicles.

[Medical Oncology] The authors summarize evolving strategies to target BCSCs, which have become a pivotal aspect of therapeutic development. They explore a variety of approaches, including targeting specific tumor surface markers, transporters, heat shock proteins, and critical signaling pathways like Notch, Akt, Hedgehog, KLF4, and Wnt/β-catenin.

[Cell And Bioscience] Scientists introduce the disease-related functions of goblet cells, their relationship with Crohn's disease, their possible mechanisms, and current Crohn's disease treatments targeting goblet cells.

[Development] Investigators highlight successes from some of the hPSC-based trials reporting early signs of efficacy and discuss common challenges in clinical translation of cell therapies.