HIV-1-Associated Left Ventricular Cardiac Dysfunction in Humanized Mice

Longitudinal echocardiography was used to assess whether NOD.Cg-Prkdc^scidIl2rgt^m1Wjl/SzJ mice reconstituted with human hematopoietic stem cells and infected with HIV-1ADA could recapitulate the salient features of HIV-1 infection.