A Biomimetic Engineered Bone Platform for Advanced Testing of Prosthetic Implants

To build a testing platform for advanced characterization of bone implants, investigators anchored model prosthetic titanium and stainless steel implants into decellularized bone scaffolds, seeded the implant-scaffold constructs with induced MSCs, and cultured the samples in an osteogenic environment in the presence of osteogenic inducing factors to grow bone tissue in vitro.