The authors showed that dietary raffinose metabolism to fructose couples stress-induced gut microbial remodeling to intestinal stem cells renewal and epithelial homeostasis.
[Nature Communications]
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Hou, Y., Wei, W., Guan, X., Liu, Y., Bian, G., He, D., Fan, Q., Cai, X., Zhang, Y., Wang, G., Zheng, X., & Hao, H. (2021). A diet-microbial metabolism feedforward loop modulates intestinal stem cell renewal in the stressed gut. Nature Communications, 12(1), 271. https://doi.org/10.1038/s41467-020-20673-4 Cite