Lentivirus-mediated overexpression, as well as antisense oligonucleotide-based silencing, modulated H19 in vitro. In vivo analyses used constitutive H19 knockout mice.
[Journal of the American Society of Nephrology]
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Haddad, G., Kölling, M., Wegmann, U. A., Dettling, A., Seeger, H., Schmitt, R., Soerensen-Zender, I., Haller, H., Kistler, A. D., Dueck, A., Engelhardt, S., Thum, T., Mueller, T. F., Wüthrich, R. P., & Lorenzen, J. M. (2021). Renal AAV2-Mediated Overexpression of Long Non-Coding RNA H19 Attenuates Ischemic Acute Kidney Injury Through Sponging of microRNA-30a-5p. Journal of the American Society of Nephrology. https://doi.org/10.1681/ASN.2020060775 Cite