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Pulmonary Cell NewsInvestigators proposed that geminin overexpression in normal mammary epithelial cells promoted the generation of TNBC metastatic precursors that home specifically to lungs by upregulating LGR5 expression and promoting stemness, intravasation, and extravasation in these precursors.
[Cancer Gene Therapy]
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Sami, E., Bogan, D., Molinolo, A., Koziol, J., & ElShamy, W. M. (2021). The molecular underpinning of geminin-overexpressing triple-negative breast cancer cells homing specifically to lungs. Cancer Gene Therapy, 1–22. https://doi.org/10.1038/s41417-021-00311-x Cite
