Researchers used an in vitro model of muscle cell ischemia in which primary human skeletal myoblasts were exposed to hypoxic conditions for 6 hours.
[Scientific Reports]
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El Baradie, K. B. Y., Khan, M. B., Mendhe, B., Waller, J., O’Brien, F., & Hamrick, M. W. (2021). The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia–reperfusion in vivo. Scientific Reports, 11(1), 6152. https://doi.org/10.1038/s41598-021-85753-x Cite