Discovery of a Novel RORγ Antagonist with Skin-Restricted Exposure for Topical Treatment of Mild to Moderate Psoriasis

By
Justin.choi
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To alleviate the potential safety concerns, identifying compounds with skin-restricted exposure amenable for topical use was of great interest.
[Scientific Reports]
Liu, S., Liu, D., Shen, R., Li, D., Hu, Q., Yan, Y., Sun, J., Zhang, F., Wan, H., Dong, P., Feng, J., Zhang, R., Li, J., Zhang, L., & Tao, W. (2021). Discovery of a novel RORγ antagonist with skin-restricted exposure for topical treatment of mild to moderate psoriasis. Scientific Reports, 11(1), 9132. https://doi.org/10.1038/s41598-021-88492-1 Cite
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