Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell NewsInvestigators improve the understanding of the role of histone modifications in osteogenic differentiation and describe its potential as a therapeutic target for osteogenic differentiation-related diseases.
[Cell Death Discovery]
6807162 {6807162:VWVHCE6K} apa 50 1 161831 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-1acfafd97d8e42a2fceaa38efebbeda7%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22VWVHCE6K%22%2C%22library%22%3A%7B%22id%22%3A6807162%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Li%20et%20al.%22%2C%22parsedDate%22%3A%222021-05-03%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELi%2C%20K.%2C%20Han%2C%20J.%2C%20%26amp%3B%20Wang%2C%20Z.%20%282021%29.%20Histone%20modifications%20centric-regulation%20in%20osteogenic%20differentiation.%20%3Ci%3ECell%20Death%20Discovery%3C%5C%2Fi%3E%2C%20%3Ci%3E7%3C%5C%2Fi%3E%281%29%2C%201%26%23x2013%3B8.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41420-021-00472-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41420-021-00472-6%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6807162%26amp%3Bitem_key%3DVWVHCE6K%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Histone%20modifications%20centric-regulation%20in%20osteogenic%20differentiation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kun%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jinxiang%22%2C%22lastName%22%3A%22Han%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ziqiang%22%2C%22lastName%22%3A%22Wang%22%7D%5D%2C%22abstractNote%22%3A%22Histone%20modification%20critically%20contributes%20to%20the%20epigenetic%20control%20of%20gene%20expression%20by%20changing%20the%20configuration%20of%20chromatin%20and%20modifying%20the%20access%20of%20transcription%20factors%20to%20gene%20promoters.%20Recently%2C%20we%20observed%20that%20histone%20acetylation%20and%20crotonylation%20mediated%20the%20expression%20of%20endocytosis-related%20genes%20and%20tumor-related%20immune%20checkpoint%20genes%20by%20regulating%20the%20enrichment%20of%20signal%20transducer%20and%20activator%20of%20transcription%203%20on%20these%20gene%20promoters%20in%20Alzheimer%5Cu2019s%20disease%20and%20tumorigenesis%2C%20suggesting%20that%20histone%20modification%20plays%20an%20important%20role%20in%20disease%20development.%20Furthermore%2C%20studies%20performed%20in%20the%20past%20decade%20revealed%20that%20histone%20modifications%20affect%20osteogenic%20differentiation%20by%20regulating%20the%20expression%20of%20osteogenic%20marker%20genes.%20In%20this%20review%2C%20we%20summarize%20and%20discuss%20the%20histone%20modification-centric%20regulation%20of%20osteogenic%20gene%20expression.%20This%20review%20improves%20the%20understanding%20of%20the%20role%20of%20histone%20modifications%20in%20osteogenic%20differentiation%20and%20describes%20its%20potential%20as%20a%20therapeutic%20target%20for%20osteogenic%20differentiation-related%20diseases.%22%2C%22date%22%3A%222021-05-03%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41420-021-00472-6%22%2C%22ISSN%22%3A%222058-7716%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41420-021-00472-6%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-05-03T22%3A01%3A15Z%22%7D%7D%5D%7D
Li, K., Han, J., & Wang, Z. (2021). Histone modifications centric-regulation in osteogenic differentiation. Cell Death Discovery, 7(1), 1–8. https://doi.org/10.1038/s41420-021-00472-6 Cite
