Clinical Significance of Circulating Tumor Cell Related Markers in Patients with Epithelial Ovarian Cancer before and after Adjuvant Chemotherapy

Using quantitative real-time PCR, the authors evaluated the expression of EPCAM, MUC1, CEA, HE4 and CA125 mRNAs, as putative markers of circulating tumor cells, in the blood of 51 epithelial ovarian cancer patients before and/or after adjuvant chemotherapy.