Investigators evaluated the hypothesis that myofibroblastic (activated) hepatic stellate cells and liver fibrosis could be safely reduced by inhibiting the cysteine/glutamate antiporter xCT.
[Liver International]
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Du, K., Oh, S. H., Dutta, R. K., Sun, T., Yang, W.-H., Chi, J.-T. A., & Diehl, A. M. (n.d.). Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury. Liver International, n/a(n/a). https://doi.org/https://doi.org/10.1111/liv.14945 Cite