Loss of FCHSD1 Leads to Amelioration of Chronic Obstructive Pulmonary Disease

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Researchers showed that the expression level of FCH and double SH3 domains 1 (FCHSD1) was drastically increased in mice in response to elastase instillation, an experimental model of chronic obstructive pulmonary disease. FCHSD1 is a member of the F-BAR family with two SH3 domains.
[Proceedings of the National Academy of Sciences of the United States of America]
Abstract