Similarities and Differences between IL11 and IL11RA1 Knockout Mice for Lung Fibro-Inflammation, Fertility and Craniosynostosis

By
Justin.choi
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0
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Scientists generated IL11 knockout (Il11−/−) mice that were born in expected ratios and have normal hematological profiles. Lung fibroblasts from Il11−/− mice were resistant to pro-fibrotic stimulation with TGFβ1.
[Scientific Reports]

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