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Pulmonary Cell NewsScientists immortalized HUVECs and fibroblasts (FBs) by exogenously expressing human telomerase reverse transcriptase to obtain stable endothelial cell and FB sources for microvascular networks formation in vitro.
[Biomaterials]
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Wan, Z., Zhang, S., Zhong, A. X., Shelton, S. E., Campisi, M., Sundararaman, S. K., Offeddu, G. S., Ko, E., Ibrahim, L., Coughlin, M. F., Liu, T., Bai, J., Barbie, D. A., & Kamm, R. D. (2021). A robust vasculogenic microfluidic model using human immortalized endothelial cells and Thy1 positive fibroblasts. Biomaterials, 276, 121032. https://doi.org/10.1016/j.biomaterials.2021.121032 Cite
