SERS Quantification of Galunisertib Delivery in Colorectal Cancer Cells by Plasmonic-Assisted Diatomite Nanoparticles

The multifunctional capability of a proposed nanosystem is demonstrated by investigating the efficient Galunisertib delivery, the enhanced epithelial-to-mesenchymal transition reversion in colorectal cancer cells and the intracellular quantification of drug release with a sub-femtogram resolution by surface-enhanced Raman spectroscopy (SERS).