NewslettersHematopoiesis NewsUncategorizedTargeting Leukemia-Specific Dependence on the De Novo Purine Synthesis PathwayBy Justin.choi - August 3, 2021016Treatment of human acute myeloid leukemia (AML) cells with a PAICS inhibitor suppressed their proliferation by inhibiting DNA synthesis and promoting apoptosis and had anti-leukemic effects in AML PDX models.[Leukemia] 7992332 5FC8Y3RQ items 1 apa 0 default asc 1 165223 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/Abstract